Thibaud Gerfaud
SENIOR PROCESS CHEMIST & PROJECT MANAGER
process chemist
project manager
Chemistry expert
Pharmaceutical and cosmetic ingredients
Biopolymers
41 years old
Rennes (35000) France
Available soon
Available
Highly skilled organic chemist with more than 10 year experience in medicinal and process chemistry, I am a team player, strongly committed to innovation. I am involved in various R&D projects in the field of dermatology and aesthetic solutions, providing expertise in the development of small molecules for topical applications but also in the development of innovative dermal fillers.
I am currently leading a team involved in route selection and optimization for the synthesis of Active Pharmaceuticals Ingredients (APIs) from 100g to 5Kg GMP. My main strength includes route selection and optimization, route scouting, team and project management (CRO and CMOs), solid form selection, impurities identification…
My major interests include the research and development of new products for health and beauty applications and the production of fine and high-specialty chemicals and naturals extracts.
I am currently leading a team involved in route selection and optimization for the synthesis of Active Pharmaceuticals Ingredients (APIs) from 100g to 5Kg GMP. My main strength includes route selection and optimization, route scouting, team and project management (CRO and CMOs), solid form selection, impurities identification…
My major interests include the research and development of new products for health and beauty applications and the production of fine and high-specialty chemicals and naturals extracts.
Team Leader, chemical development
Nestlé Skin Health
Since 2015
Sophia-Antipolis
France
- Selection, optimization and scale-up of chemical routes toward Active Pharmaceutical Ingredients from gram to multikilogram scale in a GMP environment
- Management of technicians and research associates
- Project team representative in cross functional teams
- Subcontracting activities to CRO/CDMOs
- Support to late stage development and manufacturing, troubleshooting (transfer, DoE, CPP, genotoxic impurities, degradation impurities…)
- Innovative dermal fillers based on hyaluronic acid
Process chemist, Chemical Development
Nestlé Skin Health
June 2012
to January 2015
Sophia-Antipolis
France
- Selection, optimization and scale-up of chemical routes toward Active Pharmaceutical Ingredients from gram to multikilogram scale
- Support to medicinal chemistry
- Impurity identification, characterization and synthesis
- Solid form characterization and selection, safety studies (calorimetry)
- Transfer to Kilo-Lab
Medicinal Chemist
Sanofi
March 2007
to August 2007
Internship
Montpellier
France
- Synthesis and characterization of pharmacologically active compounds for Central Nervous System
Process Chemist
GlaxoSmithKline
September 2005
to August 2006
Internship
Stevenage
United Kingdom
- Total syntheses of stable labelled molecules within the Isotope Chemistry group
Natural Products synthesis and methodologies
Master of Science & Chemical Engineer degree
Ecole Nationale Supérieure de Chimie de Montpellier
September 2003
to August 2007
Biomolecular engineering & organic chemistry
- retrosynthetic analysis
- route selection and optimization
- scale-up
- biocatalysis
- design of experiments
- safety studies
- solid form characterization and selection
- continuous flow
- organometallics
- heterocyclic chemistry
- asymmetric synthesis
- polymer synthesis
- photoredox chemistry
- polysaccharide modification and characterization
- critical process parameters definition
- impurity identification and synthesis
- GMP part II
- ICH M7
- ICH Q3A-D
- CTD module 3
- NMR
- GC / HPLC / SFC / Mass Spec
- MALDI / SEC
- IR / DSC/ XRPD
- Office / MS Project
- Chemdraw
- SciFinder / Reaxys
- MNova / TopSpin
- MODDE
- Mirabilis / Zeneth
- French (native)
- English (fluent)
- Spanish (fluent)
