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Thibaud Gerfaud

Thibaud Gerfaud

SENIOR PROCESS CHEMIST & PROJECT MANAGER

process chemist
project manager
Chemistry expert
Pharmaceutical and cosmetic ingredients
Biopolymers
41 years old
Rennes (35000) France
Available soon Available
Highly skilled organic chemist with more than 10 year experience in medicinal and process chemistry, I am a team player, strongly committed to innovation. I am involved in various R&D projects in the field of dermatology and aesthetic solutions, providing expertise in the development of small molecules for topical applications but also in the development of innovative dermal fillers.

I am currently leading a team involved in route selection and optimization for the synthesis of Active Pharmaceuticals Ingredients (APIs) from 100g to 5Kg GMP. My main strength includes route selection and optimization, route scouting, team and project management (CRO and CMOs), solid form selection, impurities identification…

My major interests include the research and development of new products for health and beauty applications and the production of fine and high-specialty chemicals and naturals extracts.
Resume created on DoYouBuzz
  • Selection, optimization and scale-up of chemical routes toward Active Pharmaceutical Ingredients from gram to multikilogram scale in a GMP environment
  • Management of technicians and research associates
  • Project team representative in cross functional teams
  • Subcontracting activities to CRO/CDMOs
  • Support to late stage development and manufacturing, troubleshooting (transfer, DoE, CPP, genotoxic impurities, degradation impurities…)
  • Innovative dermal fillers based on hyaluronic acid
Learn more
  • Selection, optimization and scale-up of chemical routes toward Active Pharmaceutical Ingredients from gram to multikilogram scale
  • Support to medicinal chemistry
  • Impurity identification, characterization and synthesis
  • Solid form characterization and selection, safety studies (calorimetry)
  • Transfer to Kilo-Lab
  • Synthesis and characterization of pharmacologically active compounds for Central Nervous System
  • Total syntheses of stable labelled molecules within the Isotope Chemistry group

Post-Doc

ETH Zürich

January 2011 to May 2012
β-oligopeptides & Molecular machines

Ph.D

Institut de Chimie des Substances Naturelles

September 2007 to December 2010
Natural Products synthesis and methodologies

Master of Science & Chemical Engineer degree

Ecole Nationale Supérieure de Chimie de Montpellier

September 2003 to August 2007
Biomolecular engineering & organic chemistry
  • retrosynthetic analysis
  • route selection and optimization
  • scale-up
  • biocatalysis
  • design of experiments
  • safety studies
  • solid form characterization and selection
  • continuous flow
  • organometallics
  • heterocyclic chemistry
  • asymmetric synthesis
  • polymer synthesis
  • photoredox chemistry
  • polysaccharide modification and characterization
  • critical process parameters definition
  • impurity identification and synthesis
  • GMP part II
  • ICH M7
  • ICH Q3A-D
  • CTD module 3
  • NMR
  • GC / HPLC / SFC / Mass Spec
  • MALDI / SEC
  • IR / DSC/ XRPD
  • Office / MS Project
  • Chemdraw
  • SciFinder / Reaxys
  • MNova / TopSpin
  • MODDE
  • Mirabilis / Zeneth
  • French (native)
  • English (fluent)
  • Spanish (fluent)