Rodrick MONTJEAN, Ph.D
R&D and preclinical development manager
44 years old
Driving License
Suresnes (92150) France
Employed
Open to opportunities
Strong background in bone diseases, virology, neurosciences, nephrology
Holder of a Ph.D in Biochemistry, Cellular and Molecular Biology, I have been focused on the preclinical development of therapeutic molecules, the elucidation of the mechanisms of action of these molecules and the discovery of the mechanisms involved in human pathologies (osteoarthritis, genetic brain and kidney diseases).
In this context, beyond technical skills, I have developed soft skills which allowed me to carry out the missions I have been entrusted :
The development of therapeutic molecules is still topical and remains a public health challenge in which I still want to get involved as a preclinical R&D project manager.
Holder of a Ph.D in Biochemistry, Cellular and Molecular Biology, I have been focused on the preclinical development of therapeutic molecules, the elucidation of the mechanisms of action of these molecules and the discovery of the mechanisms involved in human pathologies (osteoarthritis, genetic brain and kidney diseases).
In this context, beyond technical skills, I have developed soft skills which allowed me to carry out the missions I have been entrusted :
- Management skills :
- Supervision of CROs
- Coordination of expert networks
- Team supervision
- Scientific project management
- Communication skills :
- Reporting
- Written and oral presentation of data
- Redaction of scientific projects and documents
- Scientific skills :
- Study design
- Development of procedures
- Bibliographic and technological survey
- Project review
The development of therapeutic molecules is still topical and remains a public health challenge in which I still want to get involved as a preclinical R&D project manager.
Research associate
Necker Hospital (INSERM U983)
January 2010
to February 2012
Full-time
Paris
France
- Mission :
- Study the normal and pathological role of nephrocystins 1 and 4 genes that are associated with nephronophthisis.
- Study the normal and pathological role of nephrocystins 1 and 4 genes that are associated with nephronophthisis.
- Management skills :
- Scientific project management (timelines, budget, risks)
- National and International collaboration (France, Denmark)
- Scientific project management (timelines, budget, risks)
- Communication skills :
- Project reporting to the supervisor
- Presentation and discussion of data internally and externally (4 poster presentations at international meetings)
- Scientific documents redaction (2 published scientific articles, 4 abstracts and 4 posters)
- Participation in scientific articles reviewing
- Project reporting to the supervisor
- Scientific skills :
- Design and development of GLP experimental procedures
- Analyses and interpretation of results
- Team working and troubleshooting abilities
- Literature survey
- Design and development of GLP experimental procedures
- Publications :
- Inversin/Nephrocystin-2 is required for fibroblast polarity and directional cell migration.
Veland IR, R Montjean, Eley L, Pedersen LB, SF Pedersen, Schwab A, Goodship J, Saunier S, ST Christensen
PLoS One. 2013 Apr 8, 8(4).
http://www.ncbi.nlm.nih.gov/pubmed/23593172
- INF2 mutations in Charcot-Marie-Tooth disease with glomerulopathy.
Boyer O, Nevo F, Plaisier E Funalot B Gribouval O, Benoit G, Cong EH, Arrondel C, Head MJ, Montjean R, Richard L, Karras A, Pouteil-Noble C, Balafrej L Bonnardeaux A Canaud G Charasse C Dantal J, Deschenes G, Deteix P, Dubourg O, Petiot P, Pouthier D Leguern E, Guiochon-Mantel A, Broutin I, Gubler MC, Saunier S, Ronco P, Vallat JM, Alonso MA, Antignac C Mollet G.
N Engl J Med. 2011 Dec 22; 365 (25):2377-88.
http://www.ncbi.nlm.nih.gov/pubmed/22187985
- Inversin/Nephrocystin-2 is required for fibroblast polarity and directional cell migration.
- Oral communication :
- Nephrocystin-1 and nephrocystin-4 regulate the Wnt pathway and are required for ciliogenesis and epithelial morphogenesis
Helori Gaudé, Céline Burcklé, Rodrick Montjean, Flora Silbermann, Emilie Montenont, Marion Delous, Christine Vesque, Cécile Jeanpierre, Alexandre Benmerah, Philippe Bastin, Corinne Antignac, Sylvie Schneider-Maunoury and Sophie Saunier
ASN, kidney week 2011 (Philadelphia, USA. 10th-13th november 2011).
https://www.asn-online.org/education/kidneyweek/archives/past.aspx
- Nephrocystin-1 and nephrocystin-4 regulate the Wnt pathway and are required for ciliogenesis and epithelial morphogenesis
- Poster communications :
- Nephrocystin-1, nephrocystin-4 and nephrocystin-8 regulate Dishevelled and the Wnt pathway and are required for ciliogenesis and epithelial morphogenesis.
Helori Gaudé, Rodrick Montjean, Flora Silbermann, Valentina Grampa, Céline Burcklé, Emilie Montenont, Marion Delous, Christine Vesque, Cécile Jeanpierre, Corinne Antignac, Fabiola Terzi ,Sylvie Schneider-Maunoury, Sophie Saunier
Cilia 2012, 1st international scientific conference (London, UK. 17th-18th may 2012).
http://www.eventbrite.com/e/cilia-2012-1st-international-scientific-conference-tickets-2201013290
- Nephrocystin-1 and nephrocystin-4 : role in cell migration, adhesion and Rho GTPases activation.
Helori Gaudé, Rodrick Montjean, Flora Silbermann, Emilie Montenont, Céline Burcklé, Marion Delous, Corinne Antignac and Sophie Saunier.
6èmes journées «Cils, flagelles, centrosomes» (Lyon, France. 15th-16th novembrer 2011).
- Loss of NPHP1 and NPHP4 in MDCK cells leads to an over activation of Rho GTPases and actin cytoskeleton reorganization
Rodrick Montjean, Flora Silbermann, Helori-Maël Gaudé, Marion Delous, Corinne Antignac and Sophie Saunier
5èmes journées «Cils, flagelles, centrosomes» (Dourdan, France. 20th-21th october 2010).
- Nephrocystin-1, nephrocystin-4 and nephrocystin-8 regulate Dishevelled and the Wnt pathway and are required for ciliogenesis and epithelial morphogenesis.
