Rodrick MONTJEAN, Ph.D
R&D and preclinical development manager
44 years old
Driving License
Suresnes (92150) France
Employed
Open to opportunities
Strong background in bone diseases, virology, neurosciences, nephrology
Holder of a Ph.D in Biochemistry, Cellular and Molecular Biology, I have been focused on the preclinical development of therapeutic molecules, the elucidation of the mechanisms of action of these molecules and the discovery of the mechanisms involved in human pathologies (osteoarthritis, genetic brain and kidney diseases).
In this context, beyond technical skills, I have developed soft skills which allowed me to carry out the missions I have been entrusted :
The development of therapeutic molecules is still topical and remains a public health challenge in which I still want to get involved as a preclinical R&D project manager.
Holder of a Ph.D in Biochemistry, Cellular and Molecular Biology, I have been focused on the preclinical development of therapeutic molecules, the elucidation of the mechanisms of action of these molecules and the discovery of the mechanisms involved in human pathologies (osteoarthritis, genetic brain and kidney diseases).
In this context, beyond technical skills, I have developed soft skills which allowed me to carry out the missions I have been entrusted :
- Management skills :
- Supervision of CROs
- Coordination of expert networks
- Team supervision
- Scientific project management
- Communication skills :
- Reporting
- Written and oral presentation of data
- Redaction of scientific projects and documents
- Scientific skills :
- Study design
- Development of procedures
- Bibliographic and technological survey
- Project review
The development of therapeutic molecules is still topical and remains a public health challenge in which I still want to get involved as a preclinical R&D project manager.
PhD fellow
Cochin Institute (INSERM U567)
November 2004
to November 2008
Full-time
Paris
France
- Mission :
- Elucidate the molecular and cellular mechanisms involved in the renal features of the Lowe syndrome.
- Elucidate the molecular and cellular mechanisms involved in the renal features of the Lowe syndrome.
- Management skills :
- Scientific project management (timelines)
- National collaboration
- Students supervision
- In charge of cell culture reagents (testing, inventory management)
- Scientific project management (timelines)
- Communication skills :
- Project reporting to the supervisor
- Presentation and discussion of data internally and externally (7 poster presentations at national and international meetings)
- Scientific documents redaction (1 published scientific article, 7 abstracts and 7 posters)
- Writing of 4 scientific projects for funds (4 grants obtained via Association pour la Recherche sur le Cancer, Fondation pour la Recherche Médicale, Conseil Régional de la Martinique, French Lowe Syndrome Association)
- Project reporting to the supervisor
- Scientific skills :
- Design and development of GLP experimental procedures
- Analyses and interpretation of results
- Team working and troubleshooting abilities
- Literature survey
- Design and development of GLP experimental procedures
- Trainings :
- Scientific images edition with Photoshop software
INSERM
June 2006
- Fire training and handling of fire extinguishers
Faculty of Medicine Paris Descartes
May 2006
- Awareness of the prevention of occupational hazards in research laboratories
INSERM
November 2005
- Scientific images edition with Photoshop software
- Publications :
The iodide transport NIS Regulates cell motility and invasiveness by interacting with the RhoGEF LARG cancer.
Claire Lacoste, Julie Herve Myriam Bou Nader, Moniaux Nicolas, Alexandre Dos Santos, Yannick Valogne, Rodrick Montjean, Dorseuil Olivier, Didier Samuel, Doris Cassio, Carla Portulano, Nancy Carrasco, Christian Bréchot & Jamila Faivre.
Cancer Res. 1 November 2012, 72 (21) :5505-15.
http://www.ncbi.nlm.nih.gov/pubmed/22962269 - Poster communications:
Upregulation of the sodium iodide symporter in cholangiocarcinoma is associated with increased cell migration and invasion
C. Lacoste, J. Herve, N. Moniaux, F. Faitot, A. Dos Santos, R. Montjean, O. Dorseuil, D. Samuel, D. Cassio, C. Brechot, J. Faivre
American Association for the Study of Liver Diseases: Liver Meeting (Boston, USA. 29th oct- 2nd november 2010)
http://www.hepmag.com/conference/aasld2010.shtml
Implication of OCRL1-A, the Lowe syndrome protein, in trafficking and signaling in human neuronal cells
Michaël Trichet, Rodrick Montjean, Pierrette Desbois, Gérard Gacon, Olivier Dorseuil
Mental Retardation: from genes to synapses, functions and dysfunctions (Roscoff, France. 7th-11th November 2010).
http://www.anae-revue.org/article-conference-jacques-monod-sur-le-retard-mental---7-11-octobre-2010-57038516.html
Syndrome Oculo-Cérébro-Rénal de Lowe et protéine Ocrl1 : étude dans les cellules du système nerveux et du cristallin
Michaël Trichet, Rodrick Montjean, Pierrette Desbois, Gérard Gacon, Olivier Dorseuil.
11éme forum de l'école doctorale Gc2iD (Rueil-Malmaison, France. 20th-21th march 2008).
Rôle physiologique d'OCRL1, la protéine altérée dans le syndrome de Lowe, à la membrane plasmique de fibroblastes cutanés
Rodrick Montjean, Adèle Faucherre, Michaël Trichet, Pierrette Desbois, Gérard Gacon et Olivier Dorseuil
10éme forum de l'école doctorale Gc2iD (Rueil-Malmaison, France. 30th-31th march 2007).
Role of Ocrl1, the Lowe protein, in fibroblasts plasma membrane
Rodrick Montjean, Adèle Faucherre, Michaël Trichet, Pierrette Desbois, Gérard Gacon, Olivier Dorseuil.
Cell migration in development and disease (Paris, France. 20th-21th November 2006).
Etude des mécanismes moléculaires d’action d’Ocrl1 (PIP 5 phosphatase et RhoGAP) à la membrane plasmique des fibroblastes
Rodrick Montjean, Adèle Faucherre, Pierrette Desbois, Gérard Gacon, Olivier Dorseuil
Colloque des «petites protéines G» (Toulouse, France. May 2005).
Interaction de la protéine OCRL1 avec les GTPases Rho et conséquences fonctionnelles dans les cellules de patients Lowe
A. Faucherre, R. Montjean, P.Desbois, V. Satre , J. Lunardi , O. Dorseuil, G. Gacon
Colloque «GIS maladies rares» (30th-31th may 2005).
http://www.myobase.org/opac/index.php?lvl=notice_display&id=47473
