Votre navigateur est obsolète !

Pour une expériencenet et une sécurité optimale, mettez à jour votre navigateur. Mettre à jour maintenant

×

Rodrick MONTJEAN, Ph.D

Rodrick MONTJEAN, Ph.D

R&D and preclinical development manager

44 years old
Driving License
Suresnes (92150) France
Employed Open to opportunities
Strong background in bone diseases, virology, neurosciences, nephrology

Holder of a Ph.D in Biochemistry, Cellular and Molecular Biology, I have been focused on the preclinical development of therapeutic molecules, the elucidation of the mechanisms of action of these molecules and the discovery of the mechanisms involved in human pathologies (osteoarthritis, genetic brain and kidney diseases).

In this context, beyond technical skills, I have developed soft skills which allowed me to carry out the missions I have been entrusted :
  • Management skills :
  • Supervision of CROs
  • Coordination of expert networks
  • Team supervision
  • Scientific project management

  • Communication skills :
  • Reporting
  • Written and oral presentation of data
  • Redaction of scientific projects and documents

  • Scientific skills :
  • Study design
  • Development of procedures
  • Bibliographic and technological survey
  • Project review

The development of therapeutic molecules is still topical and remains a public health challenge in which I still want to get involved as a preclinical R&D project manager.
Resume created on DoYouBuzz
  • Missions :
    Preclinical development of RNA-based antiviral molecules targeting arboviruses: from design to preclinical regulatory package
  • Management skills :
    • Search for CROs, academic collaborators
    • Contracts set up and management
    • Team projects management
    • Scientific project management (timelines, budget, risks)
    • Quality control of the studies (GLP, GMP)
  • Communication skills :
    • Projects reporting to the CSO, partners and collaborators
    • Presentation and discussion of data at internal and international meetings
    • Scientific documents redaction
    • Writing of a scientific project for funds (BpiFrance-Deeptech
    • Propose and write a preclinical development plan
  • Scientific skills :
    • Identify project objectives
    • From hit to lead (RNA)
    • Study plans definition and design
    • Design and development of GLP experimental procedures
    • Analyses and interpretation of results
    • Team working and troubleshooting abilities
    • Literature and technologic survey
Detailed Description
  • Achievements :
    Identification of 20 candidate antiviral molecules (Zika, Dengue, Chikungunya)
    Design, follow-up and completion of 2 in vitro efficacy studies, 2 in vivo efficacy studies
    Management of an international network of 10 CROs
    Review of 10 CRO study reports
    1 grant obtained (€1.2 M; Bpifrance Deeptech)
Company Description
Meletios Therapeutics’ aim is to fulfill the urgent and large unmet medical need for broad spectrum treatments against current and emerging viral infections.

This French biotech company was created in April 2020 by a team of high level scientists and experienced biotech managers.

One of our first drug candidate has confirmed its broad-spectrum potential in in vitro and in vivo models on the coronavirus family and influenza H1N1, demonstrating a dual antiviral and anti-inflammatory activity. This molecule will now be developed and tested in order to meet regulatory requirements and enter clinical phase II.

Several drug candidates from Meletios portfolio are currently being tested both in vitro and in vivo and will expand our range of antiviral molecules on different RNA viruses.

Meletios Therapeutics’ goal is to become a global leader in the fight against emerging viral infections by developing innovative broad-spectrum therapeutic solutions.
Company website
  • Missions :
    • Preclinical phase management for the lead candidate molecule (REG-O3) in the frame of osteoarthritis therapeutics
    • Identification of the competencies needed for the clinical phase and international network of experts implementation
    • Clinical trial phase design in collaboration with the Chief Scientific Officer (CSO)
    • Elucidation of the mechanism of action of REG-O3 internally
  • Management skills :
    • Search for CROs, academic collaborators and partnership with other SMEs
    • Contracts set up and management
    • Coordination of the international network for the writing of regulatory documents (study reports, IMPD)
    • Team projects management
    • Scientific project management (timelines, budget, risks)
    • Quality control of the studies (GLP, GMP)
    • Implementation of the quality system in the company
  • Communication skills :
    • Projects reporting to the CSO, partners and collaborators
    • Writing of a Scientific Technical Advice to the Belgian (FAMHP) and European (EMA) Health authorities
    • Presentation and discussion of data at internal and international meetings
    • Scientific documents redaction
    • Writing of a scientific project for European funds (Eureka-Eurostars)
  • Scientific skills :
    • Study plans definition and design
    • Design and development of GLP experimental procedures
    • Analyses and interpretation of results
    • Team working and troubleshooting abilities
    • Literature and technologic survey
    • Review of scientific projects involving animals (member of the ethics committee on animal experimentation n°80)
Detailed Description
  • Achievements:
    • Management of an international network of 8 CROs, an in-house team of 2 engineers and 3 academic teams
    • Design, follow-up and completion of 10 preclinical studies, including 3 regulatory studies (hemolytic test, PK/PD, toxicology)
    • Review of 10 CRO study reports
    • Writing and/or reviewing of 40 internal study reports
    • Implementation of 20 internal procedures (SOPs)
    • Preparation of a scientific and technical advice (STA) to Belgian and European health authorities
    • Implementation of a corporate quality system and regular internal meetings
    • Development of an animal model of traumatic osteoarthritis in collaboration with a CRO
    • Review of 3 projects involving animals (member of the CEEA no. 80)
    • Writing and publication of 1 article in the Plos One journal
    • Writing of 4 annual reports, 9 abstracts and 5 posters
    • 2 oral presentations in plenary sessions at international meetings (OARSI and ICRS)
    • Preparation and submission of a project for European funding (Eureka-Eurostars: €1.9 M)
  • Trainings :- ISO 9001 quality systemOctober 2019
    • Certificate of competence for animal experimentation - design and implementation of proceduresEcole nationale vétérinaire d'AlfortSeptember 2017
  • Publication :- REG-O3 Chimeric Peptide Combining Growth Hormone and Somatostatin Sequences Improves Joint Function and Prevents Cartilage Degradation in Rat Model of Traumatic Knee Osteoarthritis.Rodrick Montjean, Sonia Escaich, Raffaello Paolini, Claude Carelli, Sébastien Pirson, Thibaut Neutelings, Yves Henrotin, Christelle Vêtu.
    PLoS One. 2020 Apr14;15(4):e0231240.
    https://pubmed.ncbi.nlm.nih.gov/32287299
  • Oral Communications :- REG-O3 Chimeric Peptide combining Growth Hormone and Somatostatin sequences slows down Traumatic Knee Osteoarthritis Progression in Rat.Rodrick Montjean, Sonia Escaich, Raffaello Paolini, Claude Carelli, Yves Henrotin, Christelle Vêtu.
    ICRS meeting 5th-8th october 2019 (Vancouver, Canada).
    https://www.emedevents.com/c/medical-conferences-2019/icrs-2019-world-congress-vancouver

    • New chimeric peptides regulating IGF-1 show significant therapeutic effect on anterior cruciate ligament transection rabbit model of osteoarthritis.Rodrick Montjean, Sonia Escaich, Raffaello Paolini, Claude Carelli, Yves Henrotin, Christelle Vêtu.
      OARSI meeting 26th-29th april 2018 (Liverpool, UK).
      https://www.oarsi.org/events/oarsi-2018-world-congress-0
  • Poster Communications :

    • Chimeric Peptide combining both Growth Hormone and Somatostatin sequences (REG-O3) Improves Function and Prevents Cartilage Degradation in Rat Model of Osteoarthritis.Rodrick Montjean, Sonia Escaich, Raffaello Paolini, Claude Carelli, Yves Henrotin, Christelle Vêtu.
      OARSI meeting 2nd-5th may 2019 (Toronto, Canada).
      https://www.oarsi.org/event/OARSI-2019-world-congress


    • Le peptide chimérique REG-O3 réduit la douleur et protège le cartilage chez le rat souffrant d’arthrose après méniscectomie partielle et section du ligament croisé.Rodrick Montjean, Sonia Escaich, Claude Carelli, Yves Henrotin, Christelle Vêtu.
      31e congrès français de rhumatologie 9th-11th december 2018 (Paris, France).
      https://sfr.larhumatologie.fr/agenda/31e-congres-francais-rhumatologie

    • REG-O3, new chimeric peptides regulating IGF-1 pathway: significant therapeutic effect on ACLT rabbit model of osteoarthritis.Raffaello PAOLINI, Rodrick MONTJEAN and Christelle VETU.
      ICRS meeting 9th-12th april 2018 (Macau, China).
      https://10times.com/icrs-qa
Company Description
Based at BIOCITECH the technology park of life science of Paris North area. The company is engaged in the research, development and licensing of innovative synthetic molecules for use in human therapies. Its mission is to grant licenses of innovative molecules in a pharmaceutical company after the establishment of a phase II clinical record.
Company website
  • Mission :
    • Elucidation of the genetics, molecular and cellular mechanisms of the neurological features in the frame of OCRL mutations (Lowe syndrome vs Dent disease-2)
  • Management skills :
    • Technical team supervision (2 technicians, 3 students)
    • Scientific project management (timelines, budget, risks)
    • National and International collaboration (France, Germany)
    • In charge of consumable (inventory management)
    • In charge of a wild-field microscope
  • Communication skills :
    • Project reporting to the supervisor
    • Presentation and discussion of data internally and externally (6 poster presentations at both national/international meetings)
    • Data presentation to financial support organizations (3 oral communications)
    • Scientific documents redaction (4 published scientific articles, 9 abstracts and 6 posters)
    • Writing of 3 scientific projects for funds (3 grants obtained via Orange Foundation, Jérôme Lejeune Foundation, French Lowe Syndrome Association)
  • Scientific skills :
    • Design and development of GLP experimental procedures
    • Analyses and interpretation of results
    • Team working and troubleshooting abilities
    • Literature survey
  • Training :
    • Basis of Image J software
      Cochin Institute
      December 2012
  • Publications :
    • Ptchd1 deficiency induces excitatory synaptic and cognitive dysfunctions in mouse.
      Ung DC, Iacono G, Méziane H, Blanchard E, Papon MA, Selten M, van Rhijn JR, Montjean R, Rucci J, Martin S, Fleet A, Birling MC, Marouillat S, Roepman R, Selloum M, Lux A, Thépault RA, Hamel P, Mittal K, Vincent JB, Dorseuil O, Stunnenberg HG, Billuart P, Nadif Kasri N, Hérault Y, Laumonnier F.
      Mol Psychiatry. 2018 May;23(5):1356-1367.
      https://www.ncbi.nlm.nih.gov/pubmed/28416808

    • Functional Characterization and Rescue of a Deep Intronic Mutation in OCRL Gene Responsible for Lowe syndrome.
      Rendu J, Montjean R, Coutton C, Suri SM, Chicanne G, Petiot PA, Brocard J, Grunwald D, Rouxel FP, Payrastre B, Lunardi J, Dorseuil O, Marty I, Fauré
      Hum Mutat. 2017 Feb;38(2):152-159.
      https://www.ncbi.nlm.nih.gov/pubmed/27790796

    • OCRL-mutated fibroblasts from patients with Dent-2 disease exhibit INPP5B-independent phenotypic variability relatively to Lowe syndrome cells.
      Montjean R, Aoidi R, Desbois P, Rucci J, Trichet M, Salomon R, Rendu J, Fauré J, Lunardi J, Gacon G, Billuart P, Dorseuil O.
      Hum Mol Genet. 2015 Feb 15;24(4):994-1006.
      http://www.ncbi.nlm.nih.gov/pubmed/25305077

    • X-exome sequencing of 405 unresolved families identifies seven novel intellectual disability genes.
      Hu H, Haas SA, Chelly J, Van Esch H, Raynaud M, de Brouwer AP, Weinert S, Froyen G, Frints SG, Laumonnier F, Zemojtel T, Love MI, Richard H, Emde AK, Bienek M, Jensen C, Hambrock M, Fischer U, Langnick C, Feldkamp M, Wissink-Lindhout W, Lebrun N, Castelnau L, Rucci J, Montjean R, Dorseuil O, Billuart P, Stuhlmann T, Shaw M, Corbett MA, Gardner A, Willis-Owen S, Tan C, Friend KL, Belet S, van Roozendaal KE, Jimenez-Pocquet M, Moizard MP, Ronce N, Sun R, O'Keeffe S, Chenna R, van Bömmel A, Göke J, Hackett A, Field M, Christie L, Boyle J, Haan E, Nelson J, Turner G, Baynam G, Gillessen-Kaesbach G, Müller U, Steinberger D, Budny B, Badura-Stronka M, Latos-Bieleńska A, Ousager LB, Wieacker P, Rodríguez Criado G, Bondeson ML, Annerén G, Dufke A, Cohen M, Van Maldergem L, Vincent-Delorme C, Echenne B, Simon-Bouy B, Kleefstra T, Willemsen M, Fryns JP, Devriendt K, Ullmann R, Vingron M, Wrogemann K, Wienker TF, Tzschach A, van Bokhoven H, Gecz J, Jentsch TJ, Chen W, Ropers HH, Kalscheuer VM
      Mol Psychiatry. 2016 Jan;21(1):133-48.
      http://www.ncbi.nlm.nih.gov/pubmed/25644381
  • Oral communications :
    • Syndrome de Lowe et maladie de Dent : étude fonctionnelle d’un gène modificateur
      Rodrick Montjean et Olivier Dorseuil
      Assemblée Générale de l’Association du Syndrome de Lowe (Paris, France. 19th march 2016).

    • Syndrome de Lowe et maladie de Dent: Analyses moléculaires et cellulaires comparatives de fibroblastes de patients.
      Rodrick Montjean et Olivier Dorseuil
      Assemblée Générale de l’Association du Syndrome de Lowe (Paris, France. 3rd may 2014).

    • Syndrome de Lowe : Conséquences sur les cellules du système nerveux (Analyse de la morphologie neuronale)
      Rodrick Montjean et Olivier Dorseuil
      Assemblée Générale de l’Association du Syndrome de Lowe (Paris, France. 6th april 2013)
  • Poster communications :
    • Characterization of Neuronal Morphology Associated with Inactivation of Intellectual Disability and Autism Spectrum Disorders Genes.
      R. Montjean, F. Paul, J. Rucci, M. Ramos, J. Renaud, G.Pavlovic, MC. Birling, G. Iacono, H. Stunnenberg, M. Selloum, Y. Herault, J. Chelly, O. Dorseuil and P. Billuart.
      2nd International GENCODYS Conference Integrative Networks in Intellectual Disabilities (Chania, Crete, Greece. 27th-29th April 2015,).
      http://www.gencodys.eu/conference2015/conference2015.php

    • Cellular and molecular mechanisms involved in intellectual deficiency of patients with Lowe syndrome
      Rodrick Montjean, Rifdat Aoidi, Pierrette Desbois, Justine Galissant, Julien Rucci, Michaël Trichet, Nicolas Lebrun, John Rendu, Julien Fauré, Rémi Salomon, Joël Lunardi, Jamel Chelly, Gérard Gacon, Pierre Billuart and Olivier Dorseuil.
      EMBO Conference-Autism and related disorders: From bench to bed (La Ciotat, France. 5th-8th September 2014).
      http://events.embo.org/14-brain/

    • Compensatory mechanisms between OCRL1-mutated fibroblasts from Lowe syndrome and Dent disease patients.
      Rodrick Montjean, Rifdat Aoidi, Julien Rucci, Justine Galissant, Michael Trichet, Pierrette Desbois, Joel Lunardi, Rémi Salomon, Nicolas Lebrun, Jamel Chelly, Gérard Gacon, Pierre Billuart and Olivier Dorseuil. Congress of Young Researchers- René Descartes (Paris, France. October 2013)
      http://www.jcard.fr/index.php?page=congres

    • Cognitive Disorder Genes And Neuronal Morphology Characterization
      J Rucci, R Montjean, M Ramos, J Renaud, F Laumonnier, H Stunnenberg, J Chelly, O Dorseuil, And P Billuart
      4th European Synapse Meeting (Bordeaux, France. 28th-30th August 2013)
      http://esm-bordeaux2013.risc.cnrs.fr/

    • Circadian regulations of hippocampal genes and role of Ophn1, an intellectual disability gene
      J.Renaud, R. Montjean F.Dumont, S.Jacques, J.Chelly, P. Billuart and O.Dorseuil
      Gencodys 1st international conference, Integrative networks in intellectual disabilities (Paphos, Chypre. 15-17th april 2013).
      http://www.gencodys.eu/Conference/

    • ID genes and synaptopathy
      J.Rucci, R.Montjean, M.Ramos, J.Renaud, J.Chelly, O.Dorseuil and P. Billuart
      Gencodys 1st international conference, Integrative networks in intellectual disabilities (Paphos, Chypre. 15-17th april 2013).
      http://www.gencodys.eu/Conference/
  • Mission :
    • Study the normal and pathological role of nephrocystins 1 and 4 genes that are associated with nephronophthisis.
  • Management skills :
    • Scientific project management (timelines, budget, risks)
    • National and International collaboration (France, Denmark)
  • Communication skills :
    • Project reporting to the supervisor
    • Presentation and discussion of data internally and externally (4 poster presentations at international meetings)
    • Scientific documents redaction (2 published scientific articles, 4 abstracts and 4 posters)
    • Participation in scientific articles reviewing
  • Scientific skills :
    • Design and development of GLP experimental procedures
    • Analyses and interpretation of results
    • Team working and troubleshooting abilities
    • Literature survey
  • Publications :
    • Inversin/Nephrocystin-2 is required for fibroblast polarity and directional cell migration.
      Veland IR, R Montjean, Eley L, Pedersen LB, SF Pedersen, Schwab A, Goodship J, Saunier S, ST Christensen
      PLoS One. 2013 Apr 8, 8(4).
      http://www.ncbi.nlm.nih.gov/pubmed/23593172

    • INF2 mutations in Charcot-Marie-Tooth disease with glomerulopathy.
      Boyer O, Nevo F, Plaisier E Funalot B Gribouval O, Benoit G, Cong EH, Arrondel C, Head MJ, Montjean R, Richard L, Karras A, Pouteil-Noble C, Balafrej L Bonnardeaux A Canaud G Charasse C Dantal J, Deschenes G, Deteix P, Dubourg O, Petiot P, Pouthier D Leguern E, Guiochon-Mantel A, Broutin I, Gubler MC, Saunier S, Ronco P, Vallat JM, Alonso MA, Antignac C Mollet G.
      N Engl J Med. 2011 Dec 22; 365 (25):2377-88.
      http://www.ncbi.nlm.nih.gov/pubmed/22187985
  • Oral communication :
    • Nephrocystin-1 and nephrocystin-4 regulate the Wnt pathway and are required for ciliogenesis and epithelial morphogenesis
      Helori Gaudé, Céline Burcklé, Rodrick Montjean, Flora Silbermann, Emilie Montenont, Marion Delous, Christine Vesque, Cécile Jeanpierre, Alexandre Benmerah, Philippe Bastin, Corinne Antignac, Sylvie Schneider-Maunoury and Sophie Saunier
      ASN, kidney week 2011 (Philadelphia, USA. 10th-13th november 2011).
      https://www.asn-online.org/education/kidneyweek/archives/past.aspx
  • Poster communications :
    • Nephrocystin-1, nephrocystin-4 and nephrocystin-8 regulate Dishevelled and the Wnt pathway and are required for ciliogenesis and epithelial morphogenesis.
      Helori Gaudé, Rodrick Montjean, Flora Silbermann, Valentina Grampa, Céline Burcklé, Emilie Montenont, Marion Delous, Christine Vesque, Cécile Jeanpierre, Corinne Antignac, Fabiola Terzi ,Sylvie Schneider-Maunoury, Sophie Saunier
      Cilia 2012, 1st international scientific conference (London, UK. 17th-18th may 2012).
      http://www.eventbrite.com/e/cilia-2012-1st-international-scientific-conference-tickets-2201013290

    • Nephrocystin-1 and nephrocystin-4 : role in cell migration, adhesion and Rho GTPases activation.
      Helori Gaudé, Rodrick Montjean, Flora Silbermann, Emilie Montenont, Céline Burcklé, Marion Delous, Corinne Antignac and Sophie Saunier.
      6èmes journées «Cils, flagelles, centrosomes» (Lyon, France. 15th-16th novembrer 2011).

    • Loss of NPHP1 and NPHP4 in MDCK cells leads to an over activation of Rho GTPases and actin cytoskeleton reorganization
      Rodrick Montjean, Flora Silbermann, Helori-Maël Gaudé, Marion Delous, Corinne Antignac and Sophie Saunier
      5èmes journées «Cils, flagelles, centrosomes» (Dourdan, France. 20th-21th october 2010).
  • Mission :
    • Elucidate the molecular and cellular mechanisms involved in the renal features of the Lowe syndrome.
  • Management skills :
    • Scientific project management (timelines)
    • National collaboration
    • Students supervision
    • In charge of cell culture reagents (testing, inventory management)
  • Communication skills :
    • Project reporting to the supervisor
    • Presentation and discussion of data internally and externally (1 poster presentation during a national meeting)
  • Scientific skills :
    • Design and development of GLP experimental procedures
    • Analyses and interpretation of results
    • Team working and troubleshooting abilities
    • Literature survey
  • Poster communication :
    • Renal tubular cells of Lowe patients exhibit defective albumin uptake, associated with dysregulation of a Rac GTPase pathway and alteration of Actin cytoskeleton.
      Rodrick Montjean, Michaël Trichet, Pierrette Desbois, Rémi Salomon, Joël Lunardi, Gérard Gacon and Olivier Dorseuil.
      12th annual meeting of the «club Exocytose-Endocytose» (Presqu'île de Giens, France. 4th-6th june 2009)
  • Mission :
    • Elucidate the molecular and cellular mechanisms involved in the renal features of the Lowe syndrome.
  • Management skills :
    • Scientific project management (timelines)
    • National collaboration
    • Students supervision
    • In charge of cell culture reagents (testing, inventory management)
  • Communication skills :
    • Project reporting to the supervisor
    • Presentation and discussion of data internally and externally (7 poster presentations at national and international meetings)
    • Scientific documents redaction (1 published scientific article, 7 abstracts and 7 posters)
    • Writing of 4 scientific projects for funds (4 grants obtained via Association pour la Recherche sur le Cancer, Fondation pour la Recherche Médicale, Conseil Régional de la Martinique, French Lowe Syndrome Association)
  • Scientific skills :
    • Design and development of GLP experimental procedures
    • Analyses and interpretation of results
    • Team working and troubleshooting abilities
    • Literature survey
  • Trainings :
    • Scientific images edition with Photoshop software
      INSERM
      June 2006

    • Fire training and handling of fire extinguishers
      Faculty of Medicine Paris Descartes
      May 2006

    • Awareness of the prevention of occupational hazards in research laboratories
      INSERM
      November 2005
  • Publications :
    The iodide transport NIS Regulates cell motility and invasiveness by interacting with the RhoGEF LARG cancer.
    Claire Lacoste, Julie Herve Myriam Bou Nader, Moniaux Nicolas, Alexandre Dos Santos, Yannick Valogne, Rodrick Montjean, Dorseuil Olivier, Didier Samuel, Doris Cassio, Carla Portulano, Nancy Carrasco, Christian Bréchot & Jamila Faivre.
    Cancer Res. 1 November 2012, 72 (21) :5505-15.
    http://www.ncbi.nlm.nih.gov/pubmed/22962269
  • Poster communications:
    Upregulation of the sodium iodide symporter in cholangiocarcinoma is associated with increased cell migration and invasion
    C. Lacoste, J. Herve, N. Moniaux, F. Faitot, A. Dos Santos, R. Montjean, O. Dorseuil, D. Samuel, D. Cassio, C. Brechot, J. Faivre
    American Association for the Study of Liver Diseases: Liver Meeting (Boston, USA. 29th oct- 2nd november 2010)
    http://www.hepmag.com/conference/aasld2010.shtml

    Implication of OCRL1-A, the Lowe syndrome protein, in trafficking and signaling in human neuronal cells
    Michaël Trichet, Rodrick Montjean, Pierrette Desbois, Gérard Gacon, Olivier Dorseuil
    Mental Retardation: from genes to synapses, functions and dysfunctions (Roscoff, France. 7th-11th November 2010).
    http://www.anae-revue.org/article-conference-jacques-monod-sur-le-retard-mental---7-11-octobre-2010-57038516.html

    Syndrome Oculo-Cérébro-Rénal de Lowe et protéine Ocrl1 : étude dans les cellules du système nerveux et du cristallin
    Michaël Trichet, Rodrick Montjean, Pierrette Desbois, Gérard Gacon, Olivier Dorseuil.
    11éme forum de l'école doctorale Gc2iD (Rueil-Malmaison, France. 20th-21th march 2008).

    Rôle physiologique d'OCRL1, la protéine altérée dans le syndrome de Lowe, à la membrane plasmique de fibroblastes cutanés
    Rodrick Montjean, Adèle Faucherre, Michaël Trichet, Pierrette Desbois, Gérard Gacon et Olivier Dorseuil
    10éme forum de l'école doctorale Gc2iD (Rueil-Malmaison, France. 30th-31th march 2007).

    Role of Ocrl1, the Lowe protein, in fibroblasts plasma membrane
    Rodrick Montjean, Adèle Faucherre, Michaël Trichet, Pierrette Desbois, Gérard Gacon, Olivier Dorseuil.
    Cell migration in development and disease (Paris, France. 20th-21th November 2006).

    Etude des mécanismes moléculaires d’action d’Ocrl1 (PIP 5 phosphatase et RhoGAP) à la membrane plasmique des fibroblastes
    Rodrick Montjean, Adèle Faucherre, Pierrette Desbois, Gérard Gacon, Olivier Dorseuil
    Colloque des «petites protéines G» (Toulouse, France. May 2005).

    Interaction de la protéine OCRL1 avec les GTPases Rho et conséquences fonctionnelles dans les cellules de patients Lowe
    A. Faucherre, R. Montjean, P.Desbois, V. Satre , J. Lunardi , O. Dorseuil, G. Gacon
    Colloque «GIS maladies rares» (30th-31th may 2005).
    http://www.myobase.org/opac/index.php?lvl=notice_display&id=47473

DEA student

Saint Antoine Hospital (INSERM U482)
September 2002 to July 2003
Part-time
paris
France
  • Research topic:
    Impact of PRA/PRB ratio modulation on apoptosis in breast cancer cell lines.