Expériences — Pachka HAMMAMI

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Experiences

Risk of autochtonous cases of Dengue in metropolitan France

Spread of Covid-19 in healthcare settings through healthcare works multiassignments

within and between farms spread of HEV in the french pig industry at national level

Spread of Covid-19 in healthcare settings through healthcare works multiassignments

Communication (social networks and website animation, press release and newlsletters draft and layout, template production, communication tools development, interviews, statistics, etc)
Training (risk analysis, risk mapping) and supervision of internship

Company website

https://www.caribvet.net/

http://agritrop.cirad.fr/583668/

Internship in Population dynamics modeling “Modeling the impact of meteorological and environmental factors on the population dynamics of the vectors of Rift Valley fever in Northern Botswana”

Animal and Integrated Risk Management research unit, CIRAD (Centre de coopération Internationale en Recherche Agronomique pour le Développement)

November 2013

Internship

Montpellier & Pretoria

Tools & skills: Scilab and R ; computer modeling, sensitivity analyses, dataset treatment (simulation and model adaptation)

Detailed Description

Publication in course
Following an epidemiological study highlighting the Rift Valley fever virus (RVFV) circulation in the region of the Okavango Delta in Botswana, the identification of the factors involved in the population dynamics of vectors of this disease proves to be essential. Knowledge on the epidemiological patterns leading to the emergence of RVFV outbreaks is still limited and a significant increase in the mosquito abundance remains the most likely hypothesis. The main objective of this study is to adapt a mechanist model of population dynamics for mosquitoes from this area, in order to i) determine the relative influence of temperature, rainfall and flooding on the vectors abundance and ii) to test the genericity of this model. The results of monthly mosquito catches conducted in four sites at the northwest border of the Delta between 2011 and 2012 were analysed. Four scenarii involving different combinations of environmental factors were assessed. Our main results indicate (1) the overabundance of the Culex pipiens and the very low occurrence of Aedes spp. in all sites, (2) a strong spatial variability between the catching sites, (3) a significant and equivalent influence of rainfall and flooding, (4) the genericity of the model in different environments. The implications of these results on the dynamics of fever Rift alley were discussed. This analysis is part of a study about the conditions leading to the Rift Valley fever emergence by analysing the response of vector populations to environmental change. The study highlights the importance to continue biological and field studies concerning vector dynamics and the relevance of this type of tool to describe and monitor the vector population evolution and develop surveillance and control strategies for vector-borne diseases.

Company Description

Work placement mentors:
Annelise Tran at the Maison de la télédétection in Montpellier, France.
Ferran Jori at the University of Pretoria in South Africa.

Company website

http://ur-agirs.cirad.fr/en/

Tools & skills: DNA extraction, PCR, genotyping, phenotyping ; microsatellite data analyses, genetic diversity, null alleles frequency, Hardy Weinberg, differentiation (FST, FIS, etc), Fisher's test, isolation by the distance, etc. Ssoftware : R, MicroCheker, Genepop, Structure, FreeNa, Genetix, IBDWebService.

Detailed Description

The heat waves of summers 1999 and 2003 have led to mass mortality events for various marine metazoans. In order to estimate the impact of such disturbances on these populations it is necessary to study their adaptaive and recolonization abilities.
The main objective of this study was to analyze the genetic structure of the Mediterranean yellow gorgonian, Eunicella cavolinii, in order to determine its dispersal abilities. Five microsatellite markers were studied on samples of 13 populations of the North Western Mediterranean, including different depths. Our main results indicate (1) a generalized pair-wise differentiation at relatively short distance, (2) trelatively weak genetic structure and diversity when compared with other octocorals, (3) no differentiation according to depth in the same site. The evolutionary consequences of these results are discussed in the contaxt of evolution of adaptative abilities. This analysis is part of a study on the adaptive processes in this species including the phenotypic variability in response to thermal stress and the levels of expression of candidate genes.

Company Description

Work placement mentor: Didier Aurelle

Preparation and leading of the study
Present our result during a seminar at the University of Montpellier

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Pachka HAMMAMI

PhD student - Modeling in epidemiology and ecology

Scientist - Epidemiological modelling

Scientist - Epidemiological modelling

Scientist - Epidemiological modelling

Scientist - Epidemiological modelling

VSC epidemiologist - communication manager

PhD : Peste des petits ruminants en Afrique subsaharienne -- Modélisation et analyse des stratégies de vaccination dans un contexte de bien public mondial.

Internship in Population dynamics modeling “Modeling the impact of meteorological and environmental factors on the population dynamics of the vectors of Rift Valley fever in Northern Botswana”

Internship in Evolutionary Genetics “Genetic survey of populations of the Mediterranean yellow gorgon [Eunicella cavolinii (Koch, 1887)]: connectivity and local adaptation processes in heterogeneous environment”

Student research Project (Costa Rica): Comparative study of different management strategies and their impacts on the biodiversity and the local population.