I am a BioAnalyst with more than 15 years of experience in the field of Analytical Chemistry. I have worked with Small Molecules as well as Cyclic Peptides. Enthusiastic and very dedicated, I love nothing more than a challenge when it comes to analysing a high/medium throughput ADMET assay or developing and validating a method for the analysis of PK samples.
Working with small challenging cyclic peptides in two areas: PK: method development, sample preparation and analysis by UPLC-MS/MS of in-vivo samples. ADMET: implementation of medium throughput screening platform for the analysis of Caco-2, Plasma Stability, Microsomal Stability and Protein Binding samples. The platform consists of two Waters Xevo-TQD with UPLC I-Class on the front end, which are run in parallel.
Responsible for the planning, the sample preparation and the analysis by UPLC-MS/MS of in-vivo samples. Responsible analyst in a Lead Optimisation project.
Line manager of 4 analysts. Responsible for the planning of in-vivo analysis, the sample preparation and the analysis by LC-MS/MS. Responsible analyst in a Lead Optimisation project.
Co-ordinator of in-vivo analysis. In charge of 2 analysts. Responsible analyst in a Lead Optimisation project. Initiation to metabolites identification.
