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Marine Lacroix

M.Sc. Eng., PhD student Immunology

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About Me
I am a junior scientist with a 5-year experience in biotech industry in the field of autoimmune and neurological diseases and am now looking for challenging opportunities in translational biomedical research - Available in July 2015
Resume created on DoYouBuzz
Experiences
  • Differential modulation of IL-6 signaling and effects on the immune response using therapeutic monoclonal antibodies
Detailed Description
  • Extensively studied the mechanisms of action of antibodies targeting IL-6R:
    • molecular interactions within signaling complex
    • cell-based and functional assays
    • PK studies
    • in vivo effects in models of acute and chronic inflammation like arthritis
Company website
http://www.novimmune.com/
  • The role of the P2X7 receptor in neurodegeneration and inflammation in multiple sclerosis
Detailed Description
  • Conducted independent research to evaluate the expression level and functionality of P2X7 at the blood brain barrier in murine models of multiple sclerosis, human cell lines and PBMC subsets
Company website
http://www.merckserono.com/en/index.html
  • Discrepancy & query management for phase II clinical trials to ensure integrity and completeness of clinical data using Oracle
  • Interactions with investigators
  • eCRF testing
Company website
http://www.quintiles.com/
  • Final optimization and implementation of recombinant protein N-glycans analysis by capillary gel electrophoresis
Detailed Description
    • Evaluated the reproducibility of the technique and proposed improvement recommendations
    • Reported encountered problems with the beta analysis software for further troubleshooting, in close collaboration with programmers from Max Planck Institute (DE)
    • Delivered a glycan analysis platform ready for a high-throughput and routine use
Company website
http://www.merckserono.com/en/index.html
  • M1/M2 macrophage characterization and study of their interaction with contrast agents in atherosclerosis
Detailed Description
    • Identified the macrophage population within atheromatous plaques of ApoE KO mice
    • Developed a protocol of M1/M2 differentiation from THP-1 cells
    • Collaboration on site with the Neurobiology of Myelin Disorders Laboratory (EA2966, Dr Klaus Petry, University of Bordeaux, France)
Company website
http://www.guerbet.com/en/en.html
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Resume created on DoYouBuzz