Isolation and puriication of Hematopoetic Stem Cells (HSCs)
Genetic Modification of HSCs
Differentiating HSCs into macrophages and microglia
Gene Therapy Corrects Mitochondrial Dysfunction in Hematopoietic Progenitor Cells and Fibroblasts from Coq9R239X Mice Barriocanal-Casado E, Cueto-Ureña C, Benabdellah K, Gutiérrez-Guerrero A, Cobo M, et al. (2016) Gene Therapy Corrects Mitochondrial Dysfunction in Hematopoietic Progenitor Cells and Fibroblasts from Coq9R239X Mice. PLoS ONE 11(6): e0158344. doi: 10.1371/journal.pone.0158344
Understanding of the molecular mechanisms which lead to neurodegeneration in diseases such as Parkinson's, Huntington's, or Alzheimer's disease.
Employin a wide variety of model organisms, from the simple but powerful budding yeast to mammalian cell culture and mice, to study the origin of the problems.
Experience working closely together with clinicians in order to accelerate drug discovery efforts, translating basic research into clinical applications that will improve the lives of patients
Developing novel in vivo imaging approaches based on multi-photon microscopy to observe protein misfolding and aggregation in the living brain.
Instituto de Investigación Biomédica de Málaga (IBIMA)
June 2014
to October 2014
Internship
Malaga
Spain
I worked under the supervision of Doctor Oscar Fernandez: -Head of the Neurology Department and Head of the Institute of Clinical Neurosciences of Carlos Haya University Hospital -President of the Multiple Sclerosis Spanish Foundation
Genética y farmacogenética de la esclerosis múltiple (EM).
Marcadores clínicos, biológicos y genéticos de la respuesta al tratamiento en la EM.
Mecanismos inmunológicos implicados en la patogenia de la em.
Estudio de dianas farmacológicas en el modelo murino de encefalitis autoinmune experimental (EAE).
Terapia celular con células madre mesenquimales autólogas de tejido adiposo en pacientes con Esclerosis Multiple
