Expériences — Abdoulaye SISSOKO

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Experiences

Subject: Identification of the biological targets and mechanisms of action of dihydroartemisinin (DHA) in Plasmodium falciparum
Skills acquired: parasite culture and synchronization of Plasmodium falciparum, phenotypic test (growth, resistance to drugs), organic hemisynthesis, purification methods in organic synthesis, protein-ligand interaction, interactomics, flow cytometry, teaching.

Company Description

UMR216-MERIT (Mères et enfants face aux infections tropicales)/IRD

June 21-22th, 2018: oral communication at doctoral school retreat
May 23-25th, 2018: poster presentation at the BioMalPar congress, EMBL, Heidelberg 2018.
May 17-18th, 2018: poster presentation at the congress of the French Society of Parasitology
April 15-20th, 2018: Poster presentation at the "Multilateral Intiative on Malaria" Conference in Dakar.

Since June 2017:
- Organization of scientific retreats
- Member of the jury at PhD student selection campaigns and their evaluation during the thesis
- Representation of PhD students at all decision-making meetings
Since December 2016:
- Representation of PhD student and trainees of my laboratory at all decision-making meetings

Subject: Functional study of human β-tubulin mutation associated with mental retardation in a model organism: Saccharomyces cerevisiae
Skills acquired: molecular cloning, double-hybrid system, fluorescence microscopy, western blot, β-galactosidase test, phenotypic tests (growth, resistance to drugs).

Genetic study of Francisella tularensis subsp holartica in its process of acquiring resistance against fluoroquinolones
Skills: DNA extraction, DNA assay, primary PCR, sequencing PCR, bioinformatics.