With a background in biochemistry and several years of experience in the in-vitro diagnostic field, I am currently searching for new opportunities in biotechnologies. Indeed, I am keen on using my skills in dynamic and innovative projects with medical or environmental applications. Adaptability, rigour, organisation, curiosity, dynamism and team spirit are the qualities I gained and developped all along my carrer.
Development of high-sensitive multiplex immunoassays on protein chips.
Conception and fulfilment of experiments for antibody selection, sensitivity determination and cross-reactivity detection.
Optimisation of the detection antibody labelling: NHS-biotin, lanthanides.
Detailed Description
Hybridization by FPPM (Forward-Phase Protein Microarray), detection by SIMS (Secondary-Ion Mass Spectrometry).
NHS-biotin and lanthanides labelling for the R&D team.
Documents writing: experiment protocols and reports, instructions for customers, safety data sheets.
ISO 9001 certified company.
Company Description
The aim of Biosims Technologies is to develop a high sensitive diagnostic tool. The idea is to be involved in several steps of personnalized medicine, during preclinical development, for the clinical studies monitoring or to allow an early diagnostic of serious diseases (cancer, inflammatory disease,...). In addition of this immunoassay technology, the company wants to propose diagnostic kits to customers.
Biomedical Instrumentation Engineer.
Diasys Technologies
February 2011
to December 2015
Full-time
Montpellier
France
In charge of testing in-vitro diagnostic devices.
Update and validation of the test procedures.
Coordination and involvement in the testing campaigns.
Detailed Description
Conducting testing procedures.
Collaboration with the programmers to correct mistakes and implement new features.
Update of the operator manual.
Occasional support to the service and maintenace team.
Company Description
Affiliate to the German company DiaSys Diagnostic Systems GmbH, DiaSys Technologies takes part to the conception of in vitro diagnostic devices. The company develops instruments for biochemical analysis as well as the software require to use them. It is also in charge of the validation part. Reagents are developped and manufactured in Germany.
Development of a biosensor for bacterial infections diagnostic.
Conduction measurements in biomimetic membranes.
Study of the changes occuring when analysis is performed under a continuous flow.
Detailed Description
Measurement of the sodium ions flow through a tethered bilayer membrane by impedance spectroscopy. The conduction is due to ion channels made by Gramicidin A dimers.
Effect of sample flow rate on the sensitivity of an ion channel switch bilayer sensor, CORNELL B, HANDY M, MANGIN A-G, RICHARDS R. Poster showed at the AACC Oak Ridge conference the 16th and 17th of April 2009 in Baltimore, USA (poster 14). http://www.aacc.org/events/meeting_proceeding/2009/Pages/program5201.aspx
Both computer simulations then experimentations showed the importance of using a continuous flow system.
Company Description
Surgical Diagnostics Pty. Ltd. is a medical technology company whose the aim is to develop diagnostic devices to manage risks occuring during endoscopy surgery procedures. The technique used for this project is based on ion channels incorporated into biomimetic membranes.
Creation and implication of a database to develop pesticide analysis.
Detailed Description
Collecting information to determine the analysis feasibility for each molecule, in different types of samples (water, air, soil, dry, fat or fat free food) and using different techniques (liquid or gas chromatography, mass spectrometry).
Construction of the database with the software Microsoft Access.
Editing of the instructions for a correct use of the database.
Company Description
Micropolluants Technologie is a company specialized in the titration of various chemicals such as dioxins, heavy metals, pesticides or hydrocarbons. The analysis are performed for environment and food industry. (Website in French).
