Currently working at Rubedo Life Sciences primarily in the Bioinformatics / Computational Biology team. Previously, Research Associate II at an early staged drug discovery company – DiCE Molecules in Redwood City.
I graduated from the University of Massachusetts-Amherst with an MS in Mechanical, Biomedical Engineering. I worked as a Research Assistant in the Vascular Biology and Biofluids Laboratory, and did in-vivo, ex-vivo in-vitro and in-silico translational research work. With the diverse and cross-disciplinary nature of the research, my coursework included classes from mechanical and biomedical engineering, biology, animal science and computer science disciplines.
My background is in the research connecting the fields of Engineering, Biology, and Medicine, and my skillsets include but are not limited to: Biomedical Sciences, Computational Biology, Vascular Biology, Wet lab experimentation, Monolith Chemistry, Bioinformatics, Automation + Robotics and Engineering design. I have an extensive background in both life sciences and engineering domains. I am passionate about science and unification of disciplines to solve new problems relevant in understanding and improving human life.
Part of early-staged drug discovery company focused on discovering drug-like molecules for pharmaceutical targets based on innovative DNA-programmed combinatorial chemistry synthesis platform.
Responsible for handling and optimizing the innovative monolithic affinity chromatography technology and production of DNA-encoded libraries which is the foundation of company’s technology.
Explored new manuscripts and experimented to improve affinity chromatography efficiency. Successfully improved the binding efficiency by 1.5x and updated chemistry protocols.
Assisted bioinformatics team in writing highly efficient python codes to facilitate quick downstream NGS data analysis for hit finding.
Hands-on wet laboratory experimentation experience and responsible for development of robust protocols.
Managed database and reported results to parallel teams on regular basis.
Handled responsibilities as a core member of in-house laboratory environmental health and safety (EH&S) team to overlook safe liquid and solid chemical disposals, procurement and handling of hazardous lab chemicals.
Vascular Biology and Biofluids Laboratory, UMass Amherst
December 2015
to October 2017
Amherst
United States - Massachusetts
Studied lymphatic fluid flow and lymphatic valves in-vivo in wild type and genetically modified mice.
Studied effects of flow in cardiovascular & cerebral vessels; disease metastasis including cancer.
Studied stenting, catheterization, medical devices, drugs and their effects to vasculature & disease.
Explored several manuscripts to understand mechanism, development, effects, metastasis and clinical treatment of conditions such as atherosclerosis, thrombosis, aneurysms, myocardial infarctions, and lymphedema.
Title: Pneumatically Energized and Actuated Robotic Leg (PEARL)
Designed and developed a remote operated powered exoskeleton to automate the human walking movement by combination of mechatronics, biomechanics (orthotics, kinesiology), pneumatics (air muscles), robotics, and product design.
Performed gait analysis to study leg movement and joint kinetics at hip, knee and ankle joint during walking.
Generated computer aided designs, analyzed the structure and simulated the human walking action.
Conceptualized and succeeded in manufacturing air muscles in-house and applied them as pneumatic actuators.
Collaborated with 25 multidisciplinary students to form Team Race Aces for the event BAJA– an ATV designing, fabricating and racing competition organized by SAE India.
Head of design and control system team:Designed structure and parts on CATIA and SolidWorks, analyzed using ANSYS.
Installed the entire electrical circuits and electronic paddle shifting mechanism for ATV.
Presented design and ideas in first round to qualify for final round; won ‘safest vehicle award’ at the final event.
